Andarine (S-4) 10 mg – 100 Capsules
Description
Biochem Andarine (S-4) 10 mg – 100 Capsules | Selective Androgen Receptor Modulator (SARM)
Biochem Andarine (S-4) 10 mg – 100 Capsules is an oral capsule product containing the compound andarine, also known as S-4, a nonsteroidal selective androgen receptor modulator (SARM) developed for investigation of androgen receptor activity in muscle and bone tissue.
This product contains 10 mg of andarine per capsule, with 100 capsules per package, representing 1,000 mg (1 gram) of andarine per package based on the stated formulation.
Andarine belongs to a class of experimental compounds designed to interact selectively with androgen receptors. These receptors are involved in the regulation of skeletal muscle, bone metabolism, reproductive physiology, and numerous androgen-dependent biological processes.
Unlike traditional anabolic-androgenic steroids, andarine does not possess the characteristic steroidal chemical structure of testosterone-derived compounds.
Instead, it is a synthetic nonsteroidal molecule that binds to androgen receptors and influences receptor-mediated gene transcription.
Andarine was investigated in preclinical development programs for potential applications involving muscle wasting, bone loss, and other conditions associated with reduced androgen activity.
Its development was based on the possibility of producing tissue-selective androgen receptor effects. However, tissue selectivity does not establish that andarine is free from androgen-related adverse effects.
Andarine is commonly identified by the development code S-4 and is frequently discussed alongside other selective androgen receptor modulators, including ostarine (MK-2866), ligandrol (LGD-4033), and RAD-140.
These compounds differ in their chemical structures, receptor interactions, pharmacokinetics, and available evidence.
Andarine has not been established as a safe or effective treatment for increasing muscle mass, improving athletic performance, treating osteoporosis, or managing hormonal disorders in humans.
Human clinical safety and efficacy data are insufficient to establish a therapeutic dosage, long-term safety profile, or approved medical indication.
Reports of visual disturbances, including changes in color perception and adaptation between light and darkness, are particularly associated with andarine in informal user accounts. The incidence, mechanism, and reversibility of these effects have not been adequately established in controlled human studies.
Andarine may also affect endogenous reproductive hormone regulation, liver function, lipid metabolism, and other androgen-responsive systems. The extent of these risks remains uncertain.
Andarine is prohibited in sport under the World Anti-Doping Agency's anabolic agents category.
The Biochem brand name does not independently establish pharmaceutical approval, manufacturing quality, analytical purity, or clinical suitability.
| Specification | Details |
|---|---|
| Product Name | Biochem Andarine |
| Compound Name | Andarine |
| Alternative Name | S-4 |
| Active Ingredient | Andarine |
| Compound Classification | Selective Androgen Receptor Modulator |
| Abbreviation | SARM |
| Chemical Classification | Nonsteroidal Androgen Receptor Ligand |
| Capsule Strength | 10 mg |
| Package Quantity | 100 Capsules |
| Total Active Ingredient | 1,000 mg |
| Total Active Ingredient in Grams | 1 g |
| Dosage Form | Oral Capsules |
| Molecular Formula | C₁₉H₁₈F₃N₃O₆ |
| Molecular Weight | Approximately 441.36 g/mol |
| Primary Molecular Target | Androgen Receptor |
| Receptor Family | Nuclear Steroid Hormone Receptor Family |
| Primary Pharmacological Action | Androgen Receptor Modulation |
| Molecular Mechanism | Receptor Binding and Modulation of Gene Transcription |
| Steroidal Structure | No |
| Testosterone Derivative | No |
| Aromatization to Estrogen | Not Established as an Aromatizable Substrate |
| Established Human Therapeutic Indication | None |
| Human Clinical Evidence | Limited |
| Investigated Biological Areas | Skeletal Muscle and Bone Metabolism |
| Administration Route | Oral |
| Human Oral Bioavailability | Not Reliably Established |
| Human Elimination Half-Life | Not Reliably Established |
| Human Metabolic Pathways | Incompletely Characterized |
| Major Safety Concern | Reported Visual Disturbances |
| Other Potential Risks | Hormonal, Hepatic, Cardiovascular, and Lipid-Related Effects |
| Competitive Sports Status | Prohibited Under WADA Rules |
| Pharmaceutical Approval | No Established Approval for Human Therapeutic Use |
| Capsule Excipients | Not Independently Confirmed |
| Product Purity | Not Independently Verified |
| Manufacturing Specifications | Not Independently Verified |
1. Interacts With Androgen Receptors
Andarine is a synthetic, nonsteroidal compound developed to bind to androgen receptors.
Androgen receptors are intracellular proteins that regulate the expression of genes involved in muscle, bone, reproductive physiology, and other biological processes.
Binding of an androgen receptor ligand can change receptor conformation and influence interactions with transcriptional regulatory proteins.
The resulting biological effects depend on tissue characteristics, receptor activity, and the compound's intrinsic pharmacological properties.
2. Was Developed for Tissue-Selective Androgen Receptor Activity
The development of SARMs was motivated by the possibility of influencing androgen-responsive tissues without reproducing every effect associated with traditional anabolic-androgenic steroids.
Andarine was studied in this context, particularly in relation to skeletal muscle and bone.
However, preclinical tissue-selective effects cannot be assumed to translate into a favorable human safety profile.
3. Has Been Investigated in Skeletal Muscle Research
Androgen receptor signaling contributes to the regulation of skeletal muscle protein metabolism and tissue maintenance.
Andarine has been examined in preclinical models involving androgen-responsive tissues.
These investigations do not establish that andarine safely increases muscle mass, strength, endurance, or athletic performance in humans.
4. Has Been Investigated in Bone Metabolism Research
Androgen signaling also influences bone remodeling and skeletal physiology.
Preclinical SARM research has examined whether compounds such as andarine can affect bone-related biological pathways.
Andarine has no established clinical indication for osteoporosis or fracture prevention.
5. Differs Chemically From Anabolic-Androgenic Steroids
Andarine is nonsteroidal and does not share the classical steroid nucleus found in testosterone and many anabolic-androgenic steroids.
Nevertheless, its interaction with androgen receptors means that some biological effects and safety concerns may overlap with those of other androgen-active substances.
A nonsteroidal chemical structure should not be interpreted as evidence of safety.
6. Has an Incompletely Characterized Human Pharmacokinetic Profile
Reliable, comprehensive human pharmacokinetic data for andarine are limited.
Its oral bioavailability, metabolic pathways, elimination characteristics, and clinically relevant drug interactions have not been sufficiently characterized to establish standardized human treatment regimens.
Specific numerical half-life claims circulating online should not be treated as established human pharmacokinetic facts without supporting clinical evidence.
7. Has Significant Unresolved Safety Concerns
Visual disturbances are among the most frequently discussed adverse effects associated with andarine.
Informal reports describe altered color perception, yellow-tinted vision, and difficulty adapting between bright and dark environments.
Other potential concerns include suppression of endogenous reproductive hormones, adverse lipid changes, liver injury, and cardiovascular effects.
The frequency, severity, long-term consequences, and reversibility of these effects have not been adequately established.
Andarine is not an approved treatment for muscle wasting, osteoporosis, erectile dysfunction, testosterone deficiency, or athletic performance enhancement. The 10 mg capsule strength describes the product presentation and is not a medically validated human dose.
Step 1 – Oral Capsule Administration
Andarine is presented in oral capsule form.
Following ingestion, the compound would need to dissolve and be absorbed through the gastrointestinal tract before producing systemic effects.
Human absorption characteristics for this formulation have not been independently established.
Step 2 – Distribution to Androgen-Responsive Tissues
Following systemic absorption, an androgen receptor ligand may distribute to tissues containing androgen receptors.
Potential target tissues include skeletal muscle, bone, and other androgen-responsive organs.
The tissue distribution of this specific Biochem formulation has not been established.
Step 3 – Interaction With Androgen Receptors
Andarine interacts with androgen receptors and may influence receptor conformation and transcriptional signaling.
The receptor response depends on the compound's pharmacological activity and the characteristics of the target tissue.
Step 4 – Modulation of Androgen-Responsive Gene Expression
Androgen receptor activation or modulation can influence gene expression associated with tissue metabolism and physiological regulation.
Preclinical observations cannot independently establish clinical benefits in humans.
Step 5 – Metabolism and Elimination
Following systemic exposure, andarine is expected to undergo metabolic processing and elimination.
However, reliable human data describing its metabolic pathways, elimination half-life, and clinically significant interactions remain insufficient.
The Biochem Andarine 10 mg capsule presentation includes the following product characteristics:
- Andarine (S-4) as the active compound.
- 10 mg per capsule.
- 100 capsules per package.
- 1,000 mg total active ingredient content.
- Oral capsule presentation.
- Nonsteroidal chemical classification.
- Selective androgen receptor modulator classification.
- Androgen receptor-binding activity.
- Interaction with nuclear receptor signaling.
- Modulation of androgen-responsive gene transcription.
- Preclinical investigation involving skeletal muscle.
- Preclinical investigation involving bone metabolism.
- No established human therapeutic indication.
- No validated human dosing regimen.
- Limited human clinical safety evidence.
- Incompletely characterized human pharmacokinetics.
- Reported visual disturbances.
- Potential endocrine and reproductive effects.
- Potential liver and lipid-related adverse effects.
- Prohibited status under WADA rules.
- Capsule excipients requiring confirmation.
- Identity, purity, and content uniformity requiring independent analytical verification.
The precise excipient composition, capsule appearance, manufacturing specifications, purity, and analytical content of Biochem Andarine 10 mg have not been independently verified.
The product description identifies the requested composition of 100 capsules containing 10 mg each. It does not establish regulatory authorization, clinical safety, or suitability for human administration.
United States
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Canada
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United Kingdom
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Germany
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France
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Spain
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Italy
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Portugal
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Netherlands
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Belgium
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Switzerland
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Austria
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Sweden
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Norway
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Denmark
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Finland
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Poland
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Czech Republic
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Romania
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Greece
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Ireland
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Colombia
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Argentina
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México
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Perú
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Venezuela
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Ecuador
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Biochem Andarine (S-4) 10mg | 100 Capsules | Selective Androgen Receptor Modulator
Learn about Biochem Andarine S-4 10mg, 100 capsules. This product contains andarine, a nonsteroidal selective androgen receptor modulator studied in preclinical muscle and bone research, with limited human safety data.
Biochem Andarine (S-4) 10mg | 100 Cápsulas | Modulador Selectivo del Receptor de Andrógenos
Conoce Biochem Andarine S-4 10mg, 100 cápsulas. Este producto contiene andarina, un modulador selectivo no esteroideo del receptor de andrógenos estudiado en investigaciones preclínicas de músculo y hueso, con datos limitados de seguridad en humanos.
biochem-andarine-s4-10mg-100-capsules
biochem-andarine-s4-10mg-100-capsulas
Biochem Andarine S-4 10mg, 100 oral capsules containing andarine, a nonsteroidal selective androgen receptor modulator associated with preclinical androgen receptor, muscle tissue, and bone metabolism research.
Biochem Andarine S-4 10mg, 100 cápsulas orales que contienen andarina, un modulador selectivo no esteroideo del receptor de andrógenos relacionado con estudios preclínicos de tejido muscular y metabolismo óseo.