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Testolone (RAD-140) 10 mg – 100 Capsules

Description

Biochem Testolone (RAD-140) 10 mg – 100 Capsules | Selective Androgen Receptor Modulator (SARM)

Biochem Testolone (RAD-140) 10 mg – 100 Capsules is an oral capsule product containing testolone, also known as RAD-140 or RAD140, a synthetic nonsteroidal selective androgen receptor modulator (SARM) developed for investigation of androgen receptor signaling in skeletal muscle, bone, and other androgen-responsive tissues.

This product contains 10 mg of testolone per capsule, with 100 capsules per package, representing 1,000 mg (1 gram) of testolone per package, based on the stated formulation.

Testolone belongs to a class of compounds known as selective androgen receptor modulators. These substances interact with androgen receptors and influence biological processes regulated by androgen signaling.

Androgen receptors are intracellular nuclear receptors involved in skeletal muscle physiology, bone metabolism, reproductive function, and numerous other androgen-responsive processes.

Unlike traditional anabolic-androgenic steroids, testolone does not possess the classical steroidal chemical structure found in testosterone-derived compounds.

Instead, testolone is a synthetic nonsteroidal molecule designed to interact with androgen receptors and influence receptor-mediated gene transcription.

RAD-140 was originally investigated for its potential tissue-selective androgenic and anabolic effects in experimental models.

Preclinical research examined its interactions with androgen receptors and its biological effects in skeletal muscle, bone, and other tissues.

Testolone has also entered human clinical investigation in oncology, particularly in research involving androgen receptor signaling in hormone receptor-positive breast cancer.

An investigational formulation of RAD-140, known as vosilasarm, has been studied in clinical development programs. Findings from these programs should not be assumed to apply directly to an unverified commercial capsule formulation.

Although testolone is frequently discussed in bodybuilding and athletic performance contexts, adequate clinical evidence does not establish that it safely increases muscle mass, improves strength, accelerates recovery, or enhances physical performance in healthy individuals.

Changes in androgen receptor signaling observed in laboratory and animal research do not independently establish clinically meaningful benefits in humans.

Testolone is not testosterone, recombinant growth hormone, a peptide hormone, or a conventional anabolic-androgenic steroid.

Its primary molecular mechanism involves androgen receptor modulation, distinguishing it from ibutamoren (MK-677), which acts through the ghrelin receptor, cardarine (GW-501516), which acts through PPARδ, and stenabolic (SR9009), which was developed to investigate REV-ERB-associated signaling.

Despite its intended tissue-selective properties, testolone may produce systemic endocrine effects.

Potential risks include suppression of endogenous reproductive hormone signaling, changes in lipid metabolism, liver injury, and uncertain long-term cardiovascular and reproductive effects.

Clinically significant liver injury has been reported in association with RAD-140 exposure. The identity and purity of products involved in individual reports may not always be independently confirmed.

Testolone has no established approved therapeutic indication for muscle growth, athletic performance, hormone replacement, osteoporosis, sarcopenia, or other musculoskeletal conditions.

RAD-140 is prohibited in competitive sport under World Anti-Doping Agency rules.

The Biochem brand name does not independently establish pharmaceutical approval, manufacturing quality, analytical purity, or clinical suitability.

SpecificationDetails
Product NameBiochem Testolone
Compound NameTestolone
Alternative NamesRAD-140 / RAD140
Investigational Drug NameVosilasarm
Active IngredientTestolone
Compound ClassificationSelective Androgen Receptor Modulator
AbbreviationSARM
Chemical ClassificationNonsteroidal Androgen Receptor Ligand
Capsule Strength10 mg
Package Quantity100 Capsules
Total Active Ingredient1,000 mg
Total Active Ingredient in Grams1 g
Dosage FormOral Capsules
Molecular FormulaC₂₀H₁₆ClN₅O₂
Molecular WeightApproximately 393.83 g/mol
Primary Molecular TargetAndrogen Receptor
Receptor FamilyNuclear Steroid Hormone Receptor Family
Primary Pharmacological ActionSelective Androgen Receptor Modulation
Molecular MechanismAndrogen Receptor Binding and Modulation of Gene Transcription
Steroidal StructureNo
Testosterone DerivativeNo
Primary Biological Areas InvestigatedAndrogen Signaling, Skeletal Muscle, Bone, and Oncology
Human Clinical ResearchLimited Investigational Clinical Studies
Investigated Clinical ApplicationsSelected Androgen Receptor-Related Oncology Indications
Established Human Therapeutic IndicationNone
Human Clinical EvidenceInsufficient to Establish Approved Therapeutic Use
Administration RouteOral
Oral Pharmacological ActivityInvestigated in Preclinical and Human Research
Human Elimination Half-LifeNot Reliably Established for This Formulation
Human Metabolic PathwaysNot Fully Characterized
Potential Endocrine EffectsSuppression or Alteration of Endogenous Hormonal Signaling
Potential Lipid EffectsChanges in Cholesterol and Lipoprotein Measurements
Important Safety ConcernsLiver Injury, Endocrine Effects, and Uncertain Cardiovascular Risk
Long-Term Human SafetyNot Established
Competitive Sports StatusProhibited Under WADA Rules
Pharmaceutical ApprovalNo Established Approval for Human Therapeutic Use
Capsule ExcipientsNot Independently Confirmed
Product PurityNot Independently Verified
Manufacturing SpecificationsNot Independently Verified

1. Selectively Interacts With Androgen Receptors

Testolone is a synthetic nonsteroidal compound developed to bind to androgen receptors.

Androgen receptors are intracellular proteins that regulate gene expression in response to androgenic signaling.

Following ligand binding, androgen receptors can undergo conformational changes that influence their interactions with transcriptional regulatory proteins.

These interactions affect the expression of androgen-responsive genes.

The resulting biological effects depend on tissue characteristics, receptor expression, and the pharmacological properties of the compound.

2. Was Developed for Tissue-Selective Androgen Receptor Activity

The development of SARMs was motivated by the possibility of influencing selected androgen-responsive tissues without reproducing every effect associated with traditional anabolic-androgenic steroids.

Testolone was investigated for its potential tissue-selective activity in experimental models.

Preclinical studies examined androgen receptor-mediated effects in skeletal muscle and other tissues.

However, tissue selectivity does not mean that testolone acts exclusively in muscle or bone.

Systemic endocrine, hepatic, metabolic, and cardiovascular effects remain possible.

3. Has Been Investigated in Skeletal Muscle Research

Androgen receptor signaling contributes to skeletal muscle protein metabolism and tissue maintenance.

Preclinical investigations have examined whether RAD-140 can influence androgen-responsive processes associated with skeletal muscle physiology.

Some experimental findings suggested anabolic activity in animal models.

However, these findings cannot be assumed to establish improvements in muscle mass, strength, endurance, or functional performance in humans.

Adequate controlled clinical evidence supporting testolone for muscle development in healthy individuals is unavailable.

4. Has Been Investigated in Bone and Musculoskeletal Physiology

Androgen receptors contribute to bone metabolism and musculoskeletal regulation.

Experimental research involving selective androgen receptor modulators has investigated whether tissue-selective androgen signaling could influence bone and muscle-related outcomes.

These investigations remain insufficient to establish testolone as a treatment for osteoporosis, sarcopenia, muscle wasting, or impaired physical function.

5. Has Been Investigated in Oncology Research

RAD-140 has entered clinical development under the investigational name vosilasarm.

Research has examined its potential role in selected forms of hormone receptor-positive breast cancer involving androgen receptor signaling.

The biological role of androgen receptor activation in cancer is complex and depends on tumor characteristics and molecular context.

Investigational oncology research does not establish that testolone is an approved cancer treatment.

It also does not demonstrate the safety or effectiveness of commercially marketed RAD-140 capsules.

6. Differs Chemically From Traditional Anabolic-Androgenic Steroids

Testolone does not contain the classical steroid nucleus characteristic of testosterone and many anabolic-androgenic steroids.

Nevertheless, it interacts with androgen receptors and may influence endocrine physiology.

A nonsteroidal chemical structure does not establish freedom from testosterone suppression, reproductive effects, liver injury, lipid abnormalities, or other androgen-related adverse effects.

Testolone should not be characterized as a risk-free alternative to anabolic-androgenic steroids.

7. Has Important Hepatic, Endocrine, and Long-Term Safety Concerns

Testolone has not undergone sufficient long-term human clinical investigation to establish an acceptable safety profile for general use.

Potential adverse effects include alterations in endogenous hormone regulation, changes in lipid measurements, liver injury, and uncertain cardiovascular effects.

Published reports have described clinically significant liver injury associated with RAD-140 exposure.

Potential reproductive effects and the reversibility of endocrine changes remain insufficiently characterized.

Testolone has no established approved therapeutic indication for muscle growth, athletic performance, recovery, osteoporosis, sarcopenia, or hormone replacement.

The 10 mg capsule strength describes the product presentation and does not establish a medically validated or safe human dose.

Step 1 – Oral Capsule Administration and Absorption

Testolone is presented as an oral capsule containing a stated 10 mg of RAD-140.

Following oral administration, the capsule would need to release its contents within the gastrointestinal tract.

The absorption characteristics and systemic exposure of this specific Biochem capsule formulation have not been independently established.

Step 2 – Distribution to Androgen-Responsive Tissues

Following systemic absorption, testolone may distribute to tissues containing androgen receptors.

Potential target tissues include skeletal muscle, bone, and other androgen-responsive organs.

The tissue distribution of the requested Biochem formulation has not been independently established.

Step 3 – Interaction With Androgen Receptors

Testolone binds to androgen receptors and influences receptor-associated signaling.

The resulting receptor conformation may affect interactions with transcriptional regulatory proteins.

These interactions participate in the regulation of androgen-responsive gene expression.

Step 4 – Modulation of Gene Transcription

Androgen receptor signaling can influence genes involved in tissue metabolism, cellular regulation, and musculoskeletal physiology.

The biological consequences depend on tissue characteristics, receptor activity, and individual endocrine conditions.

Preclinical observations cannot independently establish long-term clinical benefits or safety in humans.

Step 5 – Metabolism and Elimination

Following systemic exposure, testolone undergoes metabolic processing and elimination.

Its complete human metabolic pathways, elimination characteristics, and potential drug interactions have not been adequately characterized for this commercial formulation.

The pharmacokinetic characteristics of Biochem Testolone 10 mg remain unverified.

The Biochem Testolone 10 mg capsule presentation includes the following characteristics:

  • Testolone (RAD-140) as the stated active compound.
  • Alternative designation RAD140.
  • Investigational drug name vosilasarm.
  • 10 mg per capsule.
  • 100 capsules per package.
  • 1,000 mg total stated active ingredient content.
  • Oral capsule presentation.
  • Nonsteroidal chemical classification.
  • Selective androgen receptor modulator classification.
  • Androgen receptor-binding activity.
  • Modulation of androgen-responsive gene transcription.
  • Preclinical investigation of skeletal muscle physiology.
  • Preclinical investigation of tissue-selective androgen signaling.
  • Experimental research involving musculoskeletal physiology.
  • Human clinical investigation in selected oncology settings.
  • No established approved human therapeutic indication.
  • No validated safe human dosing regimen.
  • No established clinical benefit for athletic performance.
  • No established effectiveness for muscle growth in healthy individuals.
  • Potential changes in endogenous reproductive hormone regulation.
  • Potential adverse changes in lipid metabolism.
  • Reported liver injury associated with RAD-140 exposure.
  • Inadequately characterized long-term cardiovascular safety.
  • Inadequately characterized reproductive safety.
  • Prohibited status under WADA rules.
  • Capsule excipients requiring confirmation.
  • Identity, purity, and content uniformity requiring independent analytical verification.

The precise excipient composition, capsule appearance, manufacturing specifications, purity, and analytical content of Biochem Testolone 10 mg have not been independently verified.

The stated package contains 100 capsules of 10 mg each, representing 1,000 mg total stated active ingredient.

This description does not establish regulatory authorization, clinical safety, or suitability for human administration.


United States

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Canada

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United Kingdom

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Germany

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France

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Spain

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Italy

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Portugal

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Netherlands

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Belgium

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Switzerland

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Austria

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Sweden

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Norway

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Denmark

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Finland

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Poland

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Czech Republic

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Romania

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Greece

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Ireland

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Colombia

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Argentina

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México

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Perú

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Venezuela

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Ecuador

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Biochem Testolone (RAD-140) 10mg | 100 Capsules | Selective Androgen Receptor Modulator

Learn about Biochem Testolone RAD-140 10mg, 100 capsules. This product contains testolone, a nonsteroidal selective androgen receptor modulator investigated in preclinical muscle research and selected oncology studies, with important hepatic and endocrine safety concerns and no established approved therapeutic use.

Biochem Testolone (RAD-140) 10mg | 100 Cápsulas | Modulador Selectivo del Receptor de Andrógenos

Conoce Biochem Testolone RAD-140 10mg, 100 cápsulas. Este producto contiene testolone, un modulador selectivo no esteroideo del receptor de andrógenos investigado en estudios preclínicos musculares y en investigación oncológica, con importantes riesgos hepáticos y endocrinos y sin uso terapéutico aprobado establecido.

biochem-testolone-rad140-10mg-100-capsules

biochem-testolone-rad140-10mg-100-capsulas

Biochem Testolone RAD-140 10mg, 100 oral capsules containing testolone, a nonsteroidal selective androgen receptor modulator associated with preclinical research on androgen receptor signaling, skeletal muscle physiology, and investigational oncology applications.

Biochem Testolone RAD-140 10mg, 100 cápsulas orales que contienen testolone, un modulador selectivo no esteroideo del receptor de andrógenos relacionado con investigaciones preclínicas sobre señalización androgénica, fisiología muscular y aplicaciones oncológicas experimentales.